No

Vaccine

Induction of active immunity against yellow fever virus, primarily among persons traveling or living in areas where yellow fever infection exists. (Some countries require a valid international Certification of Vaccination showing receipt of vaccine; if a pregnant woman is to be vaccinated only to satisfy an international requirement, efforts should be made to obtain a waiver letter.) The WHO requires revaccination every 10 years to maintain traveler's vaccination certificate.

D

Sensitivity to egg or chick embryo protein; pregnant women, children <6 months of age unless in high risk area

Do not use in immunodeficient persons or patients receiving immunosuppressants (eg, steroids, radiation); have epinephrine available in persons with previous history of egg allergy if the vaccine must be used. Avoid use in infants <6 months and pregnant women unless travel to high-risk areas are unavoidable; avoid use in infants <4 months of age.

All serious adverse reactions must be reported to the U.S. Department of Health and Human Services (DHHS) Vaccine Adverse Event Reporting System (VAERS) 1-800-822-7967.

1% to 10%:

Central nervous system: Headache (2% to 5%)

Neuromuscular & skeletal: Myalgia (2% to 5%)

<1%: Encephalitis in very young infants (rare), anaphylaxis

Administer yellow fever vaccine at least 1 month apart from other live virus vaccines; defer vaccination for 3 weeks following immune globulin; concurrent cholera and yellow fever and concurrent hepatitis B vaccine and yellow fever vaccines may decrease immune response; separate vaccinations by 1 month, if possible; defer vaccination for 8 weeks following blood or plasma transfusion

Yellow fever vaccine is shipped with dry ice; do not use vaccine unless shipping case contains some dry ice on arrival; maintain vaccine continuously at a temperature between 0°C to 5°C (32°F to 41°F)

One dose (0.5 mL) S.C. 10 days to 10 years before travel, booster every 10 years; see Warnings/Precautions

Immunity develops by the tenth day and WHO requires revaccination every 10 years to maintain travelers' vaccination certificates

Sterilize and discard all unused rehydrated vaccine and containers after 1 hour; avoid vigorous shaking

Injection: Not less than 5.04 Log₁₀ Plaque Forming Units (PFU) per 0.5 mL