No

Antibiotic/Corticosteroid, Ophthalmic

Treatment of external ocular infection caused by susceptible gram-negative bacteria and steroid responsive inflammatory conditions of the palpebral and bulbar conjunctiva, lid, cornea, and anterior segment of the globe

B

1% to 10%:

Ocular: Lacrimation, itching, edema of eyelid, keratitis, increased intraocular pressure, glaucoma, cataract formation

Refer to individual monographs for Tobramycin and Dexamethasone

Refer to individual monographs for Dexamethasone and Tobramycin

Absorption: Absorbed into the aqueous humor

Time to peak serum concentration: 1-2 hours after instillation in the cornea and aqueous humor

Children and Adults: Ophthalmic: Instill 1-2 drops of solution every 4 hours; apply ointment 2-3 times/day; for severe infections apply ointment every 3-4 hours, or solution 2 drops every 30-60 minutes initially, then reduce to less frequent intervals

No information available to require special precautions

No effects or complications reported

Shake well before using, do not touch dropper to eye, apply light finger pressure on lacrimal sac for 1 minute following instillation; notify physician if condition fails to improve or worsens

Shake well before using, do not touch dropper to eye, apply light finger pressure on lacrimal sac for 1 minute following instillation; notify physician if condition fails to improve or worsens

Ointment, ophthalmic: Tobramycin 0.3% and dexamethasone 0.1% (3.5 g)

Suspension, ophthalmic: Tobramycin 0.3% and dexamethasone 0.1% (2.5 mL, 5 mL)