No

Diagnostic Agent, Thyroid Function

Diagnostic aid to differentiate thyroid failure; diagnosis of decreased thyroid reserve, to differentiate between primary and secondary hypothyroidism and between primary hypothyroidism and euthyroidism in patients receiving thyroid replacement

C

Coronary thrombosis, untreated Addison's disease, hypersensitivity to thyrotropin or any component

Use with caution in patients with angina pectoris or cardiac failure, patients with hypopituitarism, adrenal cortical suppression as may be seen with corticosteroid therapy; may cause thyroid hyperplasia

<1%: Tachycardia, fever, headache, menstrual irregularities, nausea, vomiting, increased bowel motility, anaphylaxis with repeated administration

Symptoms of overdose include weight loss, nervousness, sweating, tachycardia, insomnia, heat intolerance, menstrual irregularities, headache, angina pectoris, CHF

Acute massive overdose may require cardiac glycosides for CHF; fever should be controlled with the help of acetaminophen; antiadrenergic agents, particularly propranolol 1-3 mg I.V. every 6 hours or 80-160 mg/day, can be used to treat increased sympathetic activity.

No data reported

Refrigerate at 2°C to 8°C (36°F to 46°F) after reconstitution; use within 2 weeks

Stimulates formation and secretion of thyroid hormone, increases uptake of iodine by thyroid gland

Half-life: 35 minutes, dependent upon thyroid state

Elimination: Rapidly by the kidney in the urine

Adults: I.M., S.C.: 10 units/day for 1-3 days; follow by a radioiodine study 24 hours past last injection, no response in thyroid failure, substantial response in pituitary failure

No information available to require special precautions

No effects or complications reported

You will receive this medication for 3 days prior to the radiologic studies. You may experience some nausea or vomiting. Report dizziness, faintness, palpitations, or any respiratory difficulties. Pregnancy precautions: Inform prescriber if you are or intend to be pregnant.

Injection: 10 units