Yes

Adrenergic Agonist Agent; Ophthalmic Agent, Vasoconstrictor

Symptomatic relief of nasal congestion and conjunctival congestion

C

>10%:

Local: Transient stinging

Respiratory: Sneezing

1% to 10%:

Cardiovascular: Tachycardia, palpitations, hypertension, heart rate

Central nervous system: Headache

Neuromuscular & skeletal: Tremor

Ocular: Blurred vision

Increased toxicity: MAO inhibitors can cause an exaggerated adrenergic response if taken concurrently or within 21 days of discontinuing MAO inhibitor; beta-blockers can cause hypertensive episodes and increased risk of intracranial hemorrhage; anesthetics

Do not use if solution changes color or becomes cloudy

Stimulates alpha-adrenergic receptors in the arterioles of the conjunctiva and the nasal mucosa to produce vasoconstriction

Onset of decongestant effect: Intranasal: Within 4-8 hours

Duration: Ophthalmic vasoconstriction: 2-3 hours

Nasal congestion: Intranasal:

Children 2-6 years: Instill 2-3 drops of 0.05% solution every 4-6 hours as needed, no more frequent than every 3 hours

Children >6 years and Adults: Instill 2-4 drops or 3-4 sprays of 0.1% solution every 3-4 hours as needed, no more frequent than every 3 hours

Conjunctival congestion: Ophthalmic: Adults: Instill 1-2 drops in each eye 2-4 times/day

No information available to require special precautions

No effects or complications reported

Remove contact lenses before using in eye, do not use for more than 72 hours unless directed to do so; consult physician if changes in vision or visual acuity occur; do not exceed recommended dosage

Monitor blood pressure, heart rate, symptom response

Solution, as hydrochloride:

Ophthalmic: 0.05% (15 mL)