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Evening Primrose | ||
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Kava Kava | ||
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Milk Thistle | ||
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| U.S. Brand Names |
| Largon® Injection |
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| Generic Available |
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No |
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| Synonyms |
| Propiomazine Hydrochloride |
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| Pharmacological Index |
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Antianxiety Agent, Miscellaneous; Antiemetic |
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| Use |
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Relief of restlessness, nausea and apprehension before and during surgery or during labor |
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| Contraindications |
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Hypersensitivity to propiomazine |
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| Adverse Reactions |
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>10%: Central nervous system: Dizziness, drowsiness Gastrointestinal: Xerostomia 1% to 10%: Cardiovascular: Tachycardia Central nervous system: Confusion Dermatologic: Skin rash Gastrointestinal: Diarrhea, stomach pain Respiratory: Shortness of breath |
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| Drug Interactions |
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CNS depressants, epinephrine |
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| Usual Dosage |
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I.M., I.V.: Adults: 10-40 mg prior to procedure, additional may be repeated at 3-hour intervals |
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| Mental Health: Effects on Mental Status |
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Dizziness and drowsiness are common; may cause confusion; may rarely cause neuroleptic malignant syndrome |
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| Mental Health: Effects on Psychiatric Treatment |
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Propiomazine is a phenothiazine; concurrent use with other psychotropics may produce additive side effects |
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| Dental Health: Local Anesthetic/Vasoconstrictor Precautions |
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No information available to require special precautions |
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| Dental Health: Effects on Dental Treatment |
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>10% of patients experience dry mouth |
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| Dosage Forms |
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Injection, as hydrochloride: 20 mg/mL (1 mL) |
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