|
| U.S. Brand
Names |
|
| Fluoracaine®
Ophthalmic |

|
|
| Generic
Available |
|
|
Yes |

|
|
| Pharmacological Index |
|
|
Diagnostic Agent; Local Anesthetic |

|
|
| Use |
|
|
Anesthesia for tonometry, gonioscopy; suture removal from cornea; removal of
corneal foreign body; cataract extraction, glaucoma surgery |

|
|
| Pregnancy Risk
Factor |
|
|
C |

|
|
| Contraindications |
|
|
Known hypersensitivity to proparacaine or fluorescein or any component or
ester-type local anesthetics |

|
|
| Warnings/Precautions |
|
|
Use with caution in patients with cardiac disease, hyperthyroidism; for
topical ophthalmic use only; prolonged use not recommended |

|
|
| Adverse
Reactions |
|
|
1% to 10%: Local: Burning, stinging of eye
<1%: Allergic contact dermatitis, irritation, sensitization, erosion of
the corneal epithelium, conjunctival congestion and hemorrhage, keratitis,
iritis, corneal opacification |

|
|
| Drug
Interactions |
|
|
No data reported |

|
|
| Stability |
|
|
Store in tight, light-resistant containers |

|
|
| Mechanism of
Action |
|
|
Prevents initiation and transmission of impulse at the nerve cell membrane by
decreasing ion permeability through stabilizing |

|
|
| Pharmacodynamics/Kinetics |
|
|
Onset of action: Within 20 seconds of instillation
Duration: 15-20 minutes |

|
|
| Usual Dosage |
|
|
Ophthalmic surgery: Children and Adults: Instill 1 drop in each eye every
5-10 minutes for 5-7 doses
Tonometry, gonioscopy, suture removal: Adults: Instill 1-2 drops in each eye
just prior to procedure |

|
|
| Dental Health: Local
Anesthetic/Vasoconstrictor
Precautions |
|
|
No information available to require special precautions |

|
|
| Dental Health:
Effects on Dental Treatment |
|
|
No effects or complications reported |

|
|
| Patient
Information |
|
|
May slow wound healing; use sparingly, avoid touching or rubbing the eye
until anesthesia has worn off |

|
|
| Nursing
Implications |
|
|
Do not use if discolored; protect eye from irritating chemicals, foreign
bodies, and blink reflex; use eye patch if necessary |

|
|
| Dosage Forms |
|
|
Solution: Proparacaine hydrochloride 0.5% and fluorescein sodium 0.25% (2 mL,
5 mL) |

|
|
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