Yes

Antihistamine/Decongestant Combination

Temporary relief of upper respiratory symptoms associated with allergy or the common cold

C

Oral:

2-6 years: 1.25 mL every 4-6 hours, not to exceed 7.5 mL in 24 hours

6-12 years: 2.5 mL every 4-6 hours, not to exceed 15 mL in 24 hours

Children >12 years and Adults: 5 mL every 4-6 hours, not to exceed 30 mL in 24 hours

Increase dietary intake of riboflavin

Phenylephrine: Use with caution since phenylephrine is a sympathomimetic amine which could interact with epinephrine to cause a pressor response

Promethazine: No information available to require special precautions

Phenylephrine: Up to 10% of patients could experience tachycardia, palpitations, and dry mouth; use vasoconstrictor with caution

Although promethazine is a phenothiazine derivative, extrapyramidal reactions or tardive dyskinesias are not seen with the use of this drug.

See individual agents. Pregnancy/breast-feeding precautions: Inform prescriber if you are or intend to get pregnant. Breast-feeding is not recommended.

May cause drowsiness

Liquid: Promethazine hydrochloride 6.25 mg and phenylephrine hydrochloride 5 mg per 5 mL (120 mL, 240 mL, 473 mL)