Yes

Antihistamine/Antitussive

Temporary relief of coughs and upper respiratory symptoms associated with allergy or the common cold

C

Research on chicken embryos exposed to concentrations of dextromethorphan relative to those typically taken by humans has shown to cause birth defects and fetal death; more study is needed, but it is suggested that pregnant women should be advised not to use dextromethorphan-containing medications

Oral:

2-6 years: 1.25-2.5 mL every 4-6 hours up to 10 mL in 24 hours

6-12 years: 2.5-5 mL every 4-6 hours up to 20 mL in 24 hours

Adults: 5 mL every 4-6 hours up to 30 mL in 24 hours

No information available to require special precautions

Although promethazine is a phenothiazine derivative, extrapyramidal reactions or tardive dyskinesias are not seen with the use of this drug.

See individual agents. Pregnancy/breast-feeding precautions: Inform prescriber if you are or intend to get pregnant. Breast-feeding is not recommended.

Syrup: Promethazine hydrochloride 6.25 mg and dextromethorphan hydrobromide 15 mg per 5 mL with alcohol 7% (120 mL, 480 mL, 4000 mL)