No

Antifungal Agent, Topical

Topical treatment of tinea cruris (jock itch), tinea corporis (ringworm), and tinea pedis (athlete's foot)

B

Hypersensitivity to any component

For external use only

>10%: Local: Burning, stinging

1% to 10%:

Dermatologic: Erythema, itching

Local: Dryness, irritation

No data reported

Synthetic, broad-spectrum antifungal agent in the allylamine class; appears to have both fungistatic and fungicidal activity. Exhibits antifungal activity by selectively inhibiting the enzyme squalene epoxidase in a dose-dependent manner which results in the primary sterol, ergosterol, within the fungal membrane not being synthesized.

Absorption: Systemic, 6% for cream, less than or equal to 4% for gel

Half-life: 2-3 days

Elimination: Metabolites excreted in urine and feces

Adults: Topical: Apply cream once daily and gel twice daily (morning and evening) for up to 4 weeks

None noted

None noted

No information available to require special precautions

No effects or complications reported

External use only; avoid eyes, mouth, and other mucous membranes; do not use occlusive dressings unless directed to do so; discontinue if irritation or sensitivity develops; wash hands after application

External use only; avoid eyes, mouth, and other mucous membranes; do not use occlusive dressings unless directed to do so; discontinue if irritation or sensitivity develops; wash hands after application

Cream, as hydrochloride: 1% (15 g, 30 g, 60 g)

Gel, topical, as hydrochloride: 1% (20 g, 40 g, 60 g)