| U.S. Brand Names |
| Livostin® |
 |
| Generic Available |
|
No |
|
| Synonyms |
| Levocabastine Hydrochloride |
|
| Pharmacological Index |
|
Antihistamine; Antihistamine, H1 Blocker, Ophthalmic |
|
| Use |
|
Treatment of allergic conjunctivitis |
|
| Pregnancy Risk Factor |
|
C |
|
| Contraindications |
|
Hypersensitivity to any component of product; while soft contact lenses are being worn |
|
| Warnings/Precautions |
|
Safety and efficacy in children <12 years of age have not been established; not for injection; not for use in patients wearing soft contact lenses during treatment |
|
| Adverse Reactions |
|
>10%: Local: Transient burning, stinging, discomfort 1% to 10%: Central nervous system: Headache, somnolence, fatigue Dermatologic: Rash Gastrointestinal: Xerostomia Ocular: Blurred vision, eye pain, somnolence, red eyes, eyelid edema Respiratory: Dyspnea |
|
| Drug Interactions |
|
No data reported |
|
| Mechanism of Action |
|
Potent, selective histamine H1-receptor antagonist for topical ophthalmic use |
|
| Pharmacodynamics/Kinetics |
|
Absorption: Topical: Systemically absorbed |
|
| Usual Dosage |
|
Children >12 years and Adults: Instill 1 drop in affected eye(s) 4 times/day for up to 2 weeks |
|
| Mental Health: Effects on Mental Status |
|
May cause drowsiness |
|
| Mental Health: Effects on Psychiatric Treatment |
|
None reported |
|
| Dental Health: Local Anesthetic/Vasoconstrictor Precautions |
|
No information available to require special precautions |
|
| Dental Health: Effects on Dental Treatment |
|
No effects or complications reported |
|
| Patient Information |
|
Shake well before using |
|
| Nursing Implications |
|
Shake well before using |
|
| Dosage Forms |
|
Suspension, ophthalmic, as hydrochloride: 0.05% (2.5 mL, 5 mL, 10 mL) |
|
|
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