|
| Generic
Available |
|
|
Yes |

|
|
| Pharmacological Index |
|
|
Expectorant |

|
|
| Use |
|
|
Mucolytic expectorant in adjunctive treatment of bronchitis, bronchial
asthma, pulmonary emphysema, cystic fibrosis, or chronic
sinusitis |

|
|
| Pregnancy Risk
Factor |
|
|
X |

|
|
| Contraindications |
|
|
Hypersensitivity to inorganic iodides, iodinated glycerol, or any component;
pregnancy, newborns |

|
|
| Warnings/Precautions |
|
|
Use with caution in patients with thyroid disease or renal
impairment |

|
|
| Adverse
Reactions |
|
|
1% to 10%: Gastrointestinal: Diarrhea, nausea, vomiting
<1%: Headache, acne, dermatitis, acute parotitis, thyroid gland
enlargement, GI irritation, eyelid edema, pulmonary edema, hypersensitivity
|

|
|
| Overdosage/Toxicology |
|
|
Symptoms include metallic taste, swollen eyelids, sneezing, nausea, vomiting,
diarrhea |

|
|
| Drug
Interactions |
|
|
Increased toxicity: Disulfiram, metronidazole, procarbazine, MAO inhibitors,
CNS depressants, lithium |

|
|
| Mechanism of
Action |
|
|
Increases respiratory tract secretions by decreasing surface tension and
thereby decreases the viscosity of mucus, which aids in removal of the
mucus |

|
|
| Pharmacodynamics/Kinetics |
|
|
Absorption: From GI tract
Distribution: Accumulates in the thyroid gland
Elimination: In urine |

|
|
| Usual Dosage |
|
|
Oral:
Adults: 60 mg 4 times/day |

|
|
| Test
Interactions |
|
|
Thyroid function tests may be altered |

|
|
| Dental Health: Local
Anesthetic/Vasoconstrictor
Precautions |
|
|
No information available to require special precautions |

|
|
| Dental Health:
Effects on Dental Treatment |
|
|
No effects or complications reported |

|
|
| Patient
Information |
|
|
Take with a full glass of water; not for use in coughs lasting longer than 1
week or associated with a fever |

|
|
| Nursing
Implications |
|
|
Administer with plenty of fluids; elixir contains 21.75% alcohol; watch for
sedation; avoid elixir in children due to high alcohol
content |

|
|
| Dosage Forms |
|
|
Organically bound iodine in brackets
Solution: 50 mg/mL [25 mg/mL] (30 mL)
Tablet: 30 mg [15 mg] |

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