Yes

Corticosteroid, Topical

Anti-inflammatory, antipruritic, relief of inflammatory and pruritic manifestations [high potency topical corticosteroid]

C

Viral, fungal, or tubercular skin lesions, herpes simplex, known hypersensitivity to fluocinonide

Adverse systemic effects may occur when used on large areas of the body, denuded areas, for prolonged periods of time, with an occlusive dressing, and/or in infants or small children

<1%: Intracranial hypertension, acne, hypopigmentation, allergic dermatitis, maceration of the skin, skin atrophy, dry skin, itching, folliculitis, hypertrichosis, HPA suppression, Cushing's syndrome, growth retardation, burning, irritation, secondary infection

No data reported

Fluorinated topical corticosteroid considered to be of high potency. The mechanism of action for all topical corticosteroids is not well defined, however, is felt to be a combination of three important properties: anti-inflammatory activity, immunosuppressive properties, and antiproliferative actions.

Absorption: Dependent on amount applied and nature of skin at application site; ranges from ~1% in areas of thick stratum corneum (palms, soles, elbows, etc) to 36% in areas of thin stratum corneum (face, eyelids, etc); absorption is increased in areas of skin damage, inflammation, or occlusion

Distribution: Distributed throughout local skin; any absorbed drug is removed rapidly from the blood and distributed into muscle, liver, skin, intestines, and kidneys

Metabolism: Primarily in the skin; small amount absorbed into systemic circulation is metabolized primarily in the liver to inactive compounds

Elimination: By the kidneys primarily as glucuronides and sulfates, but also as unconjugated products; small amounts of metabolites are excreted in feces

Children and Adults: Topical: Apply thin layer to affected area 2-4 times/day depending on the severity of the condition. Therapy should be discontinued when control is achieved; if no improvement is seen, reassessment of diagnosis may be necessary.

No information available to require special precautions

No effects or complications reported

Do not use tight-fitting diapers or plastic pants on children being treated in the diaper area; use only as prescribed, and for no longer than the period prescribed; apply sparingly in a light film; rub in lightly; notify physician if condition being treated persists or worsens; avoid contact with eyes

Use sparingly

Cream: 0.05% (15 g, 30 g, 60 g, 120 g)

Anhydrous, emollient (Lidex®): 0.05% (15 g, 30 g, 60 g, 120 g)

Aqueous, emollient (Lidex-E®): 0.05% (15 g, 30 g, 60 g, 120 g)

Gel, topical: 0.05% (15 g, 60 g)

Lidex®: 0.05% (15 g, 30 g, 60 g, 120 g)

Ointment, topical: 0.05% (15 g, 30 g, 60 g)

Lidex®: 0.05% (15 g, 30 g, 60 g, 120 g)

Solution, topical: 0.05% (20 mL, 60 mL)

Lidex®: 0.05% (20 mL, 60 mL)