|
| U.S. Brand
Names |
|
| Van R
Gingibraid® |

|
|
| Generic
Available |
|
|
No |

|
|
| Pharmacological Index |
|
|
Adrenergic Agonist Agent; Alpha/Beta Agonist; Astringent;
Vasoconstrictor |

|
|
| Use |
|
|
Dental: Gingival retraction
Medical: None |

|
|
| Contraindications |
|
|
Patients with cardiovascular disease, hyperthyroidism, or diabetes; patients
sensitive to epinephrine; do not apply to areas of heavy or deep bleeding or
over exposed bone |

|
|
| Warnings/Precautions |
|
|
Caution should be exercised whenever using gingival retraction cords with
epinephrine since it delivers vasoconstrictor doses of racemic epinephrine to
patients; the general medical history should be thoroughly evaluated before
using in any patient |

|
|
| Adverse
Reactions |
|
|
No data reported |

|
|
| Drug
Interactions |
|
|
No data reported |

|
|
| Mechanism of
Action |
|
|
Epinephrine stimulates alpha1 adrenergic receptors to cause
vasoconstriction in blood vessels in gingiva; aluminum potassium sulfate,
precipitates tissue and blood proteins |

|
|
| Pharmacodynamics/Kinetics |
|
|
No data reported |

|
|
| Usual Dosage |
|
|
Pass the impregnated yarn around the neck of the tooth and place into
gingival sulcus; normal tissue moisture, water, or gingival retraction solutions
activate impregnated yarn. Limit use to one quadrant of the mouth at a time;
recommended use is for 3-8 minutes in the mouth. |

|
|
| Dietary
Considerations |
|
|
No data reported |

|
|
| Dental Health: Local
Anesthetic/Vasoconstrictor
Precautions |
|
|
No information available to require special precautions |

|
|
| Dental Health:
Effects on Dental Treatment |
|
|
Tissue retraction around base of the tooth (therapeutic
effect) |

|
|
| Dosage Forms |
|
|
Yarn, saturated in solution of 8% racemic epinephrine and 7% aluminum
potassium sulfate; yarn labeled type "0e" contains
0.20±0.10 mg epinephrine per inch; "1e" contains
0.40±0.20 mg per inch; "2e" contains
0.60±0.20 mg per inch |

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|
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