Yes

Adrenergic Agonist Agent; Alpha/Beta Agonist; Antidote; Bronchodilator; Vasoconstrictor

Dental: Emergency drug for treatment of anaphylactic reactions; used as vasoconstrictor to prolong local anesthesia

C

Hypersensitivity to epinephrine or any component; cardiac arrhythmias, angle-closure glaucoma

Use with caution in elderly patients, patients with diabetes mellitus, cardiovascular diseases (angina, tachycardia, myocardial infarction), thyroid disease, or cerebral arteriosclerosis, Parkinson's; some products contain sulfites as antioxidants. Rapid I.V. infusion may cause death from cerebrovascular hemorrhage or cardiac arrhythmias. Oral inhalation of epinephrine is not the preferred route of administration.

No data reported

Increased cardiac irritability if administered concurrently with halogenated inhalational anesthetics, beta-blocking agents, alpha-blocking agents

Stimulates alpha-, beta₁-, and beta₂-adrenergic receptors resulting in relaxation of smooth muscle of the bronchial tree, cardiac stimulation, and dilation of skeletal muscle vasculature; small doses can cause vasodilation via beta₂-vascular receptors; large doses may produce constriction of skeletal and vascular smooth muscle; decreases production of aqueous humor and increases aqueous outflow; dilates the pupil by contracting the dilator muscle

Absorption: Not absorbed orally

Hypersensitivity reaction:

Adults: I.M., S.C.: 0.2-0.5 mg every 20 minutes to 4 hours (single dose maximum: 1 mg)

No data reported

No information available to require special precautions

No effects or complications reported

Injection:

Adrenalin®: 0.01 mg/mL [1:100,000] (5 mL); 0.1 mg/mL [1:10,000] (3 mL, 10 mL); 1 mg/mL [1:1000] (1 mL, 2 mL, 30 mL)

Suspension (Sus-Phrine®): 5 mg/mL [1:200] (0.3 mL, 5 mL)

Solution, topical (Adrenalin®): 0.1% [1 mg/mL, 1:1000] (30 mL, 10 mL)