Yes

Analgesic, Narcotic

Produce and maintain analgesia and sedation during diagnostic or surgical procedures (neuroleptanalgesia and neuroleptanesthesia); adjunct to general anesthesia

C

Hypersensitivity to droperidol or fentanyl; patients who have taken MAO inhibitors within 14 days

>10%:

Cardiovascular: Bradycardia, mild to moderate hypotension, tachycardia

Central nervous system: Drowsiness, nausea, vomiting, postoperative drowsiness

Respiratory: Respiratory depression

1% to 10%:

Cardiovascular: Cardiac arrhythmia, orthostatic hypotension, hypertension

Central nervous system: Confusion, CNS depression, extrapyramidal reactions

Gastrointestinal: Biliary spasm

Ocular: Blurred vision

Respiratory: Respiratory depression

CNS depressant drugs may cause additive effects; may cause hypertensive crisis if given with MAO inhibitors

Children:

Premedication: I.M.: 0.03 mL/kg 30-60 minutes prior to surgery

Adjunct to general anesthesia: I.V.: Total dose: 0.05 mL/kg as slow infusion (1 mL/1-2 minutes) until sleep occurs

Adults:

Premedication: I.M.: 0.5-2 mL 30-60 minutes prior to surgery

Adjunct to general anesthesia: I.V.: 0.09-0.11 mL/kg as slow infusion (1 mL/1-2 minutes) until sleep occurs

Drowsiness is common; may cause depression or extrapyramidal symptoms; rarely may produce delirium or hallucinations

Contraindicated within 14 days of MAOIs; concurrent use with psychotropics may produce additive sedation

See individual agents. Pregnancy/breast-feeding precautions: Inform prescriber if you are or intend to get pregnant. Consult prescriber if breast-feeding.

An opioid antagonist, resuscitative and intubation equipment, and oxygen should be available

Monitor O₂ saturation, blood pressure, vital signs

Injection: Droperidol 2.5 mg and fentanyl 50 mcg per mL (2 mL, 5 mL)