| U.S. Brand Names |
| Dialose® Plus Capsule [OTC]; Diocto C®[OTC]; Diocto-K Plus®[OTC]; Dioctolose Plus®[OTC]; Disanthrol®[OTC]; DSMC Plus®[OTC]; Genasoft® Plus [OTC]; Peri-Colace®[OTC]; Pro-Sof® Plus [OTC]; Regulace®[OTC]; Silace-C®[OTC] |
 |
| Generic Available |
|
Yes |
|
| Synonyms |
| Casanthranol and Docusate; DSS With Casanthranol |
|
| Pharmacological Index |
|
Laxative/Stool Softner |
|
| Use |
|
Treatment of constipation generally associated with dry, hard stools and decreased intestinal motility |
|
| Pregnancy Risk Factor |
|
C |
|
| Adverse Reactions |
|
1% to 10%: Gastrointestinal: Intestinal obstruction, diarrhea, abdominal cramping, throat irritation |
|
| Stability |
|
Store in tight, light-resistant containers |
|
| Usual Dosage |
|
Oral: Adults: 1-2 capsules or 15-30 mL syrup at bedtime, may be increased to 2 capsules or 30 mL twice daily or 3 capsules at bedtime |
|
| Dental Health: Local Anesthetic/Vasoconstrictor Precautions |
|
No information available to require special precautions |
|
| Dental Health: Effects on Dental Treatment |
|
No effects or complications reported |
|
| Patient Information |
|
Adults: Take with a full glass of water; patients should assure proper dietary fiber and fluid intake with adequate exercise if medically appropriate; do not use if abdominal pain, nausea, or vomiting are present; laxative use should be used for a short period of time (<1 week); prolonged use may result in abuse, dependence, as well as fluid and electrolyte loss; notify physician if bleeding occurs or if constipation is not relieved |
|
| Nursing Implications |
|
Monitor bowel frequency |
|
| Dosage Forms |
|
Capsule: Dialose® Plus, Diocto-K Plus®, Dioctolose Plus®, DSMC Plus®: Docusate potassium 100 mg and casanthranol 30 mg Disanthrol®, Genasoft® Plus, Peri-Colace®, Pro-Sof® Plus, Regulace®: Docusate sodium 100 mg and casanthranol 30 mg Syrup (Diocto C®, Peri-Colace®, Silace-C®): Docusate sodium 60 mg and casanthranol 30 mg per 15 mL with alcohol 10% (240 mL, 480 mL, 4000 mL) |
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