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| U.S. Brand Names |
| Actifed® Allergy Tablet (Night) [OTC]; Banophen® Decongestant Capsule [OTC]; Benadryl® Decongestant Allergy Tablet [OTC] |
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| Generic Available |
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Yes |
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| Pharmacological Index |
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Antihistamine/Decongestant Combination |
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| Use |
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Relief of symptoms of upper respiratory mucosal congestion in seasonal and perennial nasal allergies, acute rhinitis, rhinosinusitis, and eustachian tube blockage |
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| Adverse Reactions |
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See individual agents |
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| Drug Interactions |
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See individual agents |
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| Usual Dosage |
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Adults: Oral: 1 capsule or tablet every 4-6 hours, up to 4/day |
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| Dental Health: Local Anesthetic/Vasoconstrictor Precautions |
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Use with caution since pseudoephedrine is a sympathomimetic amine which could interact with epinephrine to cause a pressor response |
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| Dental Health: Effects on Dental Treatment |
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Chronic use of antihistamines will inhibit salivary flow, particularly in elderly patients; this may contribute to periodontal disease and oral discomfort |
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| Dosage Forms |
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Capsule: Diphenhydramine hydrochloride 25 mg and pseudoephedrine hydrochloride 60 mg Tablet: Actifed® Allergy (Night): Diphenhydramine hydrochloride 25 mg and pseudoephedrine hydrochloride 30 mg Benadryl® Decongestant Allergy: Diphenhydramine hydrochloride 25 mg and pseudoephedrine hydrochloride 60 mg |
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