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| U.S. Brand Names |
| Disobrom®[OTC]; Disophrol® Chronotabs®[OTC]; Disophrol® Tablet [OTC]; Drixomed®; Drixoral®[OTC] |
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| Generic Available |
|
Yes |
|
| Synonyms |
| Pseudoephedrine and Dexbrompheniramine |
|
| Pharmacological Index |
|
Antihistamine/Decongestant Combination |
|
| Use |
|
Relief of symptoms of upper respiratory mucosal congestion in seasonal and perennial nasal allergies, acute rhinitis, rhinosinusitis and eustachian tube blockage |
|
| Pregnancy Risk Factor |
|
B |
|
| Usual Dosage |
|
Children >12 years and Adults: Oral: 1 tablet every 12 hours, may require 1 tablet every 8 hours |
|
| Dietary Considerations |
|
May be administered with food or water |
|
| Dental Health: Local Anesthetic/Vasoconstrictor Precautions |
|
Use with caution since pseudoephedrine is a sympathomimetic amine which could interact with epinephrine to cause a pressor response |
|
| Dental Health: Effects on Dental Treatment |
|
Up to 10% of patients could experience tachycardia, palpitations, and dry mouth; use vasoconstrictor with caution |
|
| Patient Information |
|
Swallow whole, do not crush or chew |
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| Nursing Implications |
|
Swallow whole, do not crush or chew |
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| Dosage Forms |
|
Tablet (Disophrol®): Dexbrompheniramine maleate 2 mg and pseudoephedrine sulfate 60 mg Timed release (Disobrom®, Disophrol® Chrontabs®, Drixomed®, Drixoral®, Histrodrix®, Resporal®): Dexbrompheniramine maleate 6 mg and pseudoephedrine sulfate 120 mg |
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