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Cyanide Antidote Kit
Pronunciation
Generic Available
Pharmacological Index
Use
Usual Dosage
Nursing Implications
Dosage Forms

Generic Available

Yes


Pharmacological Index

Antidote


Use

Treatment of cyanide poisoning


Usual Dosage

Cyanide poisoning: 0.3 mL ampul of amyl nitrite is crushed every minute and vapor is inhaled for 15-30 seconds until an I.V. sodium nitrite infusion is available. Following administration of 300 mg I.V. sodium nitrite, inject 12.5 g sodium thiosulfate I.V. (over ~10 minutes), if needed; injection of both may be repeated at 1/2 the original dose.


Nursing Implications

Sodium nitrate infusion is limited by hypotension; sodium thiosulfate infusion rate is 2.5-5 mL/minute


Dosage Forms

Kit: Sodium nitrite 300 mg/10 mL (#2); sodium thiosulfate 12.5 g/50 mL (#2); amyl nitrite 0.3 mL (#12); also disposable syringes, stomach tube, tourniquet and instructions


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