No

Antibiotic, Miscellaneous; Antidiarrheal

Treatment of diarrhea in infants and children caused by susceptible organisms, especially E. coli and Shigella, however, other agents are preferred; treatment of superficial infections of external ear canal and of mastoidectomy and fenestration cavities

C

Known hypersensitivity to colistin

Use with caution in patients with impaired renal function; some systemic absorption may occur; potential for renal toxicity exists; prolonged use may lead to superinfection

<1%: Neuromuscular blockade, nephrotoxicity, respiratory arrest, nausea, vomiting, hypersensitivity reactions, superinfections

Stable for 2 weeks when refrigerated, shake well; discard after 14 days

Polypeptide antibiotic that binds to and damages the bacterial cell membrane

Absorption: Oral: Slightly absorbed from GI tract (adults); unpredictable absorption occurs in infants, can lead to significant serum levels

Half-life: 2.8-4.8 hours, prolonged in renal insufficiency; with anuria: 48-72 hours

Elimination: ~65% to 75% excreted unchanged in urine

Diarrhea: Children: Oral: 5-15 mg/kg/day in 3 divided doses given every 8 hours

None reported

None reported

No information available to require special precautions

No effects or complications reported

Keep refrigerated, shake well, discard after 14 days

Powder for oral suspension: 25 mg/5 mL (60 mL)