Yes

Antihistamine/Decongestant/Antitussive

Temporary relief of cough associated with minor throat or bronchial irritation or nasal congestion due to common cold, allergic rhinitis, or sinusitis

C-V

C

1% to 10%:

Central nervous system: Sedation, dizziness, drowsiness, increased intracranial pressure

Gastrointestinal: Constipation, biliary tract spasm

Genitourinary: Urinary tract spasm

Miscellaneous: Physical or psychological dependence with continued use

Oral:

25-50 lb: 1.25-2.50 mL every 4-6 hours, up to 4 doses in 24-hour period

50-90 lb: 2.5-5 mL every 4-6 hours, up to 4 doses in 24-hour period

Adults: 10 mL every 4-6 hours, up to 4 doses in 24-hour period

Use with caution since pseudoephedrine is a sympathomimetic amine which could interact with epinephrine to cause a pressor response

Chlorpheniramine: Prolonged use will cause significant xerostomia

Codeine: <1%: Dry mouth

Pseudoephedrine: Up to 10% of patients could experience tachycardia, palpitations, and dry mouth; use vasoconstrictor with caution

Liquid: Chlorpheniramine maleate 2 mg, pseudoephedrine hydrochloride 30 mg, and codeine phosphate 10 mg (120 mL, 480 mL)