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> Drugs > Chlorpheniramine,
Phenylephrine, and
Methscopolamine |
| Chlorpheniramine,
Phenylephrine, and Methscopolamine |
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| U.S. Brand
Names |
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| D.A.II® Tablet; Dallergy®;
Dura-Vent/DA®; Extendryl® SR; Histor-D®
Timecelles® |
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| Generic
Available |
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Yes |
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| Pharmacological Index |
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Antihistamine/Decongestant/Anticholinergic |
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| Use |
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Relieves nasal congestion, runny nose and sneezing |
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| Usual Dosage |
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Adults: Oral: 1 capsule every 12 hours |
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| Dental Health: Local
Anesthetic/Vasoconstrictor
Precautions |
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Use with caution since phenylephrine is a sympathomimetic amine which could
interact with epinephrine to cause a pressor response |
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| Dental Health:
Effects on Dental Treatment |
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Chlorpheniramine: Prolonged use will cause significant xerostomia
Methscopolamine: Anticholinergic side effects can cause a reduction of saliva
production or secretion contributes to discomfort and dental disease (ie,
caries, oral candidiasis and periodontal disease)
Phenylephrine: Up to 10% of patients could experience tachycardia,
palpitations, and dry mouth; use vasoconstrictor with caution
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| Dosage Forms |
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Caplet, sustained release: Chlorpheniramine maleate 8 mg, phenylephrine
hydrochloride 20 mg, and methscopolamine nitrate 2.5 mg
Capsule, sustained release: Chlorpheniramine maleate 8 mg, phenylephrine
hydrochloride 10 mg, and methscopolamine nitrate 2.5 mg
Syrup: Chlorpheniramine maleate 2 mg, phenylephrine hydrochloride 10 mg, and
methscopolamine nitrate 0.625 mg per 5 mL
Tablet: Chlorpheniramine maleate 4 mg, phenylephrine hydrochloride 10 mg, and
methscopolamine nitrate 1.25 mg |
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