|
| U.S. Brand
Names |
|
| Ordrine AT® Extended Release
Capsule; Rescaps-D® S.R. Capsule; Tuss-Allergine® Modified
T.D.
Capsule; Tussogest® Extended Release
Capsule |

|
|
| Generic
Available |
|
|
Yes |

|
|
| Synonyms |
|
|
Phenylpropanolamine and Caramiphen |

|
|
| Pharmacological Index |
|
|
Antihistamine |

|
|
| Use |
|
|
Symptomatic relief of cough and nasal congestion associated with the common
cold |

|
|
| Pregnancy Risk
Factor |
|
|
C |

|
|
| Contraindications |
|
|
Concurrent MAO inhibitor therapy; bronchial asthma; severe hypertension;
hypersensitivity to caramiphen edisylate or phenylpropanolamine
hydrochloride |

|
|
| Drug
Interactions |
|
|
MAO inhibitors, TCAs, NSAIDs |

|
|
| Usual Dosage |
|
|
Oral:
2-6 years: 1/2
teaspoonful every 4 hours
6-12 years: 1 teaspoonful every 4 hours
Children >12 years and Adults: 1 capsule every 12 hours or 2 teaspoonfuls
every 4 hours |

|
|
| Mental Health: Effects
on Mental Status |
|
|
May cause restlessness or insomnia |

|
|
| Mental Health:
Effects on Psychiatric
Treatment |
|
|
Contraindicated with concurrent MAOI therapy |

|
|
| Dental Health: Local
Anesthetic/Vasoconstrictor
Precautions |
|
|
Use with caution since phenylpropanolamine is a sympathomimetic amine which
could interact with epinephrine to cause a pressor response |

|
|
| Dental Health:
Effects on Dental Treatment |
|
|
Up to 10% of patients could experience tachycardia, palpitations, and dry
mouth; use vasoconstrictor with caution |

|
|
| Patient
Information |
|
|
See individual agents. Pregnancy/breast-feeding precautions: Inform
prescriber if you are or intend to be pregnant. Consult prescriber if
breast-feeding. |

|
|
| Dosage Forms |
|
|
Capsule, timed release: Caramiphen edisylate 40 mg and phenylpropanolamine
hydrochloride 75 mg
Liquid: Caramiphen edisylate 6.7 mg and phenylpropanolamine hydrochloride
12.5 mg per 5 mL |

|
|
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|