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Tyrosine | ||
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| U.S. Brand Names |
| Bromanate® DC; Bromphen® DC w/Codeine; Dimetane®-DC; Myphetane DC®; Poly-Histine CS® |
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| Generic Available |
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Yes |
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| Synonyms |
| Codeine, Brompheniramine, and Phenylpropanolamine; Phenylpropanolamine, Brompheniramine, and Codeine |
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| Pharmacological Index |
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Antihistamine/Decongestant/Antitussive |
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| Use |
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Relief of coughs and upper respiratory symptoms, including nasal congestion, associated with allergy or the common cold |
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| Restrictions |
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C-V |
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| Pregnancy Risk Factor |
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C |
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| Drug Interactions |
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CNS depressants, MAO inhibitors, sympathomimetics, Rauwolfia alkaloids, tricyclic antidepressants, ganglionic blocking agents, propranolol |
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| Usual Dosage |
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Oral: 2-6 years: 2.5 mL every 4 hours 6-12 years: 5 mL every 4 hours Children >12 years and Adults: 10 mL every 4 hours |
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| Dental Health: Local Anesthetic/Vasoconstrictor Precautions |
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Brompheniramine: No information available to require special precautions Phenylpropanolamine: Use with caution since phenylpropanolamine is a sympathomimetic amine which could interact with epinephrine to cause a pressor response |
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| Dental Health: Effects on Dental Treatment |
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Brompheniramine: Prolonged use may decrease salivary flow Codeine: <1%: Dry mouth Phenylpropanolamine: Up to 10% of patients could experience tachycardia, palpitations, and dry mouth; use vasoconstrictor with caution |
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| Patient Information |
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See individual agents. Pregnancy/breast-feeding precautions: Inform prescriber if you are or intend to be pregnant. Do not breast-feed. |
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| Dosage Forms |
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Liquid: Brompheniramine maleate 2 mg, phenylpropanolamine hydrochloride 12.5 mg, and codeine phosphate 10 mg per 5 mL with alcohol 0.95% (480 mL) |
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