| U.S. Brand Names |
| AK-Poly-Bac® Ophthalmic; Betadine® First Aid Antibiotics + Moisturizer [OTC]; Polysporin® Ophthalmic; Polysporin® Topical |
 |
| Generic Available |
|
Yes |
|
| Canadian Brand Names |
| Bioderm®; Polytopic |
|
| Synonyms |
| Polymyxin B and Bacitracin |
|
| Pharmacological Index |
|
Antibiotic, Ophthalmic; Antibiotic, Topical |
|
| Use |
|
Treatment of superficial infections caused by susceptible organisms |
|
| Pregnancy Risk Factor |
|
C |
|
| Adverse Reactions |
|
1% to 10%: Local: Rash, itching, burning, anaphylactoid reactions, swelling and conjunctival erythema |
|
| Drug Interactions |
|
No data reported |
|
| Mechanism of Action |
|
Refer to individual monographs for Bacitracin and Polymyxin B |
|
| Usual Dosage |
|
Children and Adults: Topical ointment/powder: Apply to affected area 1-4 times/day; may cover with sterile bandage if needed |
|
| Dental Health: Local Anesthetic/Vasoconstrictor Precautions |
|
No information available to require special precautions |
|
| Dental Health: Effects on Dental Treatment |
|
No effects or complications reported |
|
| Patient Information |
|
See individual agents. Pregnancy/breast-feeding precautions: Inform prescriber if you are or intend to be pregnant. Consult prescriber if breast-feeding. |
|
| Nursing Implications |
|
Ophthalmic ointment may cause blurred vision; do not share eye medications with others Ophthalmic administration: Tilt head back, place medication in conjunctival sac and close eyes; apply light finger pressure on lacrimal sac for 1 minute following instillation |
|
| Dosage Forms |
|
Ointment: Ophthalmic: Bacitracin 500 units and polymyxin B sulfate 10,000 units per g (3.5 g) Topical: Bacitracin 500 units and polymyxin B sulfate 10,000 units per g in white petrolatum (15 g, 30 g) Powder: Bacitracin 500 units and polymyxin B sulfate 10,000 units per g (10 g) |
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