|
| U.S. Brand
Names |
|
| Children's Kaopectate®[OTC];
Diasorb®[OTC]; Kaopectate® Advanced Formula [OTC];
Kaopectate® Maximum Strength
Caplets; Rheaban®[OTC] |

|
|
| Generic
Available |
|
|
Yes |

|
|
| Pharmacological Index |
|
|
Antidiarrheal |

|
|
| Use |
|
|
Symptomatic treatment of diarrhea |

|
|
| Pregnancy Risk
Factor |
|
|
B |

|
|
| Contraindications |
|
|
Hypersensitivity to attapulgite or any component |

|
|
| Adverse
Reactions |
|
|
The powder, if chronically inhaled, can cause pneumoconiosis, since it
contains large amounts of silica |

|
|
| Drug
Interactions |
|
|
Decreased GI absorption of orally administered clindamycin, tetracyclines,
penicillamine, digoxin |

|
|
| Mechanism of
Action |
|
|
Controls diarrhea because of its absorbent action |

|
|
| Pharmacodynamics/Kinetics |
|
|
Absorption: Not absorbed from GI tract |

|
|
| Usual Dosage |
|
|
Oral:
<3 years: Not recommended
3-6 years: 750 mg/dose up to 2250 mg/24 hours
6-12 years: 1200-1500 mg/dose up to 4500 mg/24 hours
Adults: 1200-1500 mg after each loose bowel movement or every 2 hours; 15-30
mL up to 8 times/day, up to 9000 mg/24 hours |

|
|
| Mental Health: Effects
on Mental Status |
|
|
None reported |

|
|
| Mental Health:
Effects on Psychiatric
Treatment |
|
|
Concurrent use with psychotropics may produce additive GI effects
(constipation) |

|
|
| Dental Health: Local
Anesthetic/Vasoconstrictor
Precautions |
|
|
No information available to require special precautions |

|
|
| Dental Health:
Effects on Dental Treatment |
|
|
Do not give oral drugs concomitantly with Kaopectate®
due to decreased GI absorption |

|
|
| Patient
Information |
|
|
If diarrhea is not controlled in 48 hours, contact a
physician |

|
|
| Nursing
Implications |
|
|
Shake well before administering; re-evaluate cause of diarrhea if not
controlled in 48 hours; diarrhea should also be treated by diet, ie, clear
liquids, bland foods, and no dairy products for first 24-48 hours
Monitor for signs of fluid and electrolyte loss |

|
|
| Dosage Forms |
|
|
Liquid, oral concentrate: 600 mg/15 mL (180 mL, 240 mL, 360 mL, 480 mL); 750
mg/15 mL (120 mL)
Tablet: 750 mg
Chewable: 300 mg, 600 mg |

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