Yes

Otic Agent, Anti-infective; Topical Skin Product

Irrigation of the bladder; treatment of superficial bacterial infections of the external auditory canal and vagina

C

During transurethral procedures; hypersensitivity to drug or components

Not for internal intake or I.V. infusion; topical use or irrigation use only; use of irrigation in patients with mucosal lesions of urinary bladder may cause irritation; systemic acidosis may result from absorption

<1%: Systemic acidosis, urologic pain, hematuria

Irrigation (note dosage of an irrigating solution depends on the capacity or surface area of the structure being irrigated):

For continuous irrigation of the urinary bladder with 0.25% acetic acid irrigation, the rate of administration will approximate the rate of urine flow; usually 500-1500 mL/24 hours

For periodic irrigation of an indwelling urinary catheter to maintain patency, about 50 mL of 0.25% acetic acid irrigation is required

Otic: Insert saturated wick; keep moist 24 hours; remove wick and instill 5 drops 3-4 times/day

Vaginal: One applicatorful every morning and evening

Not for internal intake or I.V. infusion; topical use or irrigation use only

For continuous or intermittent irrigation of the urinary bladder, urine pH should be checked at least 4 times/day and the irrigation rate adjusted to maintain a pH of 4.5-5

Jelly vaginal: 0.921% with oxyquinolone sulfate 0.025%, ricinoleic acid 0.7%, and glycerin 5% (85 g)

Solution:

Irrigation: 0.25% (1000 mL)

Otic: Acetic acid 2% in propylene glycol (15 mL, 30 mL, 60 mL)

Kawamata M, Fujita S, and Mayumi T, "Acetic Acid Intoxication by Rectal Administration," J Toxicol Clin Toxicol, 1994, 32(3):333-6.

Penner GE, "Acid Ingestion: Toxicology and Treatment," Ann Emerg Med, 1980, 9(7):374-9.